Mechanism of Action :
Capsaicin, or 6-nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl, (6E), is a highly
selective agonist for the transient receptor potential vanilloid 1 receptor (TRPV1). The initial effect of
capsaicin is the activation of TRPV1-expressing cutaneous nociceptors, which results in pungency and
erythema due to the release of vasoactive neuropeptides.
Indication :
Capsaicin is indicated to
- temporarily relieves minor aches and pains of muscles and joints
- the treatment of peripheral neuropathic pain in adults either alone or in combination with other medicinal products for the treatment of pain.